Discuss normal cartilage architecture in terms of aggrecan & collagen


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Discuss normal cartilage architecture in terms of aggrecan & collagen


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This is a wide topic and you won’t be able to cover every aspect in 1000 words. You need to briefly discuss normal cartilage architecture in terms of aggrecan & collagen and the changes that occur in osteoarthritis. Describe metalloproteinases and their mode of action and then I suggest you focus on one particular aspect.