Explain the difference in depolarizing and nondepolarizing neuromuscular junction blockers
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Explain the difference in depolarizing and nondepolarizing neuromuscular junction blockers
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Discussion Topics, Chapter 28, Neuromuscular Junction Blocking Agents
Discussion Topics
Learning Objective(s)
1. Ms. Smith is scheduled for electroconvulsive therapy today. She has a history of narrow-angle glaucoma. You have been assigned to care for Ms. Smith during this clinical rotation.
a. Which neuromuscular junction blocking agent would you expect to be used during the procedure: succinylcholine or tubocurarine? Defend your answer.
b. Explain the difference in depolarizing and nondepolarizing neuromuscular junction blockers.
2. You are observing in the pediatric ICU and have been assigned to follow a 5-year-old who is mechanically ventilated and receiving vecuronium to prevent spontaneous respiratory effort and muscle relaxation.
a. What special nursing care considerations should this patient receive?
b. The patient is currently receiving gentamycin for an infection and aminophylline for wheezing. What are the potential implications of combining the medications with vecuronium?
