Opinion on whether you believe that genetics or environment as being the most important aspect when it comes to acquisition of diseases and disabilities or whether a combination of both are responsible

Give your opinion and support it with citations as to whether you believe that genetics or environment as being the most important aspect when it comes to acquisition of diseases and disabilities or whether a combination of both are responsible. Give examples, please. https://www.youtube.com/watch?v=FCaLJN2d1zM https://www.youtube.com/watch?v=8SDKV29NPaE