What is depression, and what is the current biogenic theory for the causes of depression?


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What is depression, and what is the current biogenic theory for the causes of depression?


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Discussion Topics, Chapter 21, Antidepressant Agents

Discussion Topics

Learning Objective(s)

1. The clinical instructor has assigned a group of students to work with patients on a special nursing unit that treats women with postpartum depression. The instructor assigns the following questions as part of the preclinical preparation.

a. What is depression, and what is the current biogenic theory for the causes of depression?

b. Describe the actions of these classes of antidepressant in a single sentence.

• TCA

• MAO inhibitors

• SSRI

2. Ms. Jones has been taking MAO inhibitors for several weeks when she calls the clinic because she has developed a severe headache, heart palpitations, dilated pupils, tachycardia, chest pain, and sweating after attending a wine and cheese tasting event.

a. These symptoms are common in what adverse condition in patients taking MAO inhibitors? What type of immediate treatment is required?

b. What adverse drug-food interactions involving MAO inhibitors can occur?

3. Your neighbor calls you and begins to discuss her child’s recent change in behavior. She states that he recently was started on the SSRI Fluoxetine (Prozac) for the treatment of depression. He is now less talkative and spending more time sleeping. She states that the dose may be too low.

a. How should you respond?